S198

Sigma

 

N6-p-Sulfophenyladenosine sodium salt

solid

Synonym:SPA, 4-[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]-benzenesulfonic acid sodium-potassium salt
Linear Formula:C16H16N5O7S · Na
Molecular Weight:445.38
MDL number:MFCD03788208

Details

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Description

Biochem/physiol ActionsA1 adenosine receptor agonist.
CautionHygroscopic. Photosensitive
Legal InformationSold under license from the National Institutes of Health.

Properties

formsolid
color off-white
solubilityDMSO: soluble
 H2O: soluble
storage temp.−20°C

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

References

referenceJacobson, K.A., et al., Synthesis and biological activity of N6-(p-sulfophenyl) alkyl and N6-Sulfoalkyl derivatives of adenosine: Water-soluble and peripherally selective adenosine agonists. J. Med. Chem. 35, 4143-4149, (1992) Abstract
 Van Schaick, E.A, et al., Metabolic and cardiovascular effects of the adenosine A1 receptor agonist N6-(p-sulfophenyl) adenosine in diabetic Zucker rats: Influence of the disease on the selectivity of action. J. Pharmacol. Exp. Ther. 287, 21-30, (1998) Abstract